In Evidence-Based Practice, a PICO question is a tool that will help you identify the most important parts of your research question.
PICO stands for:
How does the use of aspirin (I) compare to 30 minutes of daily exercise (C) in the prevention of strokes (O) in men over the age of 50 (P)?
Does daily home blood pressure monitoring (I) influence compliance with medication regimens for hypertension (O) in adults over age 60 who have hypertension (P)? (The implied C-comparison is those not monitoring their blood pressure.)
Do oral contraceptives (I) put women ages 18-30 (P) at greater risk for blood clots (O) than women ages 18-30 who use IUDs (C)?